MPH Blog

Posts for tag: Trifexis

By R. deLeon-Mims for Morena Pet Hospital
November 16, 2013
Category: Pet Safety


In response to recent concerns over the heartworm, flea and intestinal parasite prevention Trifexis, we have an excerpt from a statement from Elanco, manufacturers of Trifexis:

November 11, 2013

Since the product came to market in January 2011, all reported potential adverse events have been reported to the FDA and appropriately investigated.  There is no link established between product use and death.

We take the safety of our products very seriously and thoroughly investigate potential concerns related to product use, including the cases explored by WSB-TV.  In the instance of the three litter mate puppies, the investigation is ongoing, but based on the information we have received, there are multiple other factors associated with the unfortunate death of these puppies.  Specifically, via necropsy, all were diagnosed with myocarditis, and inflammation of the heart muscle.  It is noteworthy that with more than 50 million doses of Trifexis dispensed in the U.S. alone, there have been no breed-specific trends or patterns with a similar familial type response as seen in this case.

In the older dog, the pet’s medical history suggests the probability of conditions that were present even before the dog’s first dose of Trifexis, including a potential mass in the animal’s lungs suggested by X-ray.

These data suggest it is unlikely that Trifexis was the cause.  Further, the attending veterinarians have indicated other factors were involved.

If you have any further concerns about the use of Trifexis in your pet, or  suspect that your pet may be having a reaction, please contact our office immediately!